BIO650 - Special Topics in Bioinformatics - Home Page

Instructor: Asscociate Prof. Vasilis J Promponas. vprobon@ucy.ac.cy

Description/Goals

Lectures cover six broad areas:

• Overview of Computational Biology and Bioinformatics.
• Fundamentals of sequence comparison.
• Comparative genomics.
• Gene/protein annotation (function prediction).
• Biological networks.
• Structural bioinformatics.

During the course, students are handed (classic) papers of the field (including authoritative reviews) as well as selected recent original research articles followed by discussion groups. Papers discussing controversial issues are the basis of individual assignments resulting in oral presentations and discussion groups. A group project (2-3 students per group), using freely available or simulated real-world data and freely available tools is presented at the end of the semester (written report and oral presentation) followed by discussion.

Intended Learning Outcomes:

Students should be able to:

• Recognize the importance of different bioinformatics approaches in modern Molecular Biology, Genetics and Genomics
• Apprehend fundamental bioinformatics methods (e.g. sequence comparison, comparative genomics, network analysis)
• Identify the bioinformatics methods used in different original research papers.
• Understand the data types associated with different types of analyses.
• Assess the reproducibility of bioinformatics methods reported in the literature based on the reported protocols and data identifiers.
• Perform effective literature and reverse citation search to quickly collect information about a scientific field of interest.
• Reproduce results from select original publications based on similar data and methods.

This course is taught in English and is available to ERASMUS+/YUFE students.

General Information

Meetings for this class are organized as follows:

Lectures: Friday, 18.00-21.00 (Room 001, ΧΩΔ01 building; available to YUFE+ students online via Teams).

Tutorials/Practicals: Wednesday, 13.00-14.00 (Room 003, ΧΩΔ01 building; available to YUFE+ students online via Teams).

Class web: Class material on the web can be accessed at the

Class web page @github.io: https://vprobon.github.io/BIO6500/

Teams group (BIO650-Fall2023) [only students enrolled in BIO650 have access]

Final exam: details (e.g. date, room etc) will be arranged by the Academic Affairs and Student Welfare Service (AASWS) of the University of Cyprus (https://ucyweb.ucy.ac.cy/fmweb/en/exams-schedule).

Note: According to the UCY regulations class attendance is obligatory.

Content and Schedule

Assessment

Teaching material

Code of conduct

Communication/Contact

Bioinformatics Research Laboratory @UCY 2005-2023.